James Lafferty As Nathan Scott
Chad Michael Murray As Lucas Scott
Hilarie Burton As Peyton Sawyer
Sophia Bush As Brooke Davis
Bethany Joy Galeotti As Haley James Scott
Jackson Brundage As James Lucas Scott(Jamie)
Paul Johansson As Dan Scott
Lee Norris As Marvin McFadden(Mouth)
Moira Kelly As Karen Roe
Antwon Tanner As Skills
Craig Sheffer As Keith Scott
Barbara Alyn Woods As Deb Scott
Barry Corbin As Coach Whitey Durham
Danneel Harris As Rachel Gatina
Lisa Goldstein As Millicent
Brett Claywell As Tim Smith
Bevin Prince As Bevin Mirskey
Kate Voelgele As Mia
Tyler Hilton As Chris Keller
Torrey DeVitto As Nanny Carrie
Stephen Colletti As Chase Adams
Matt Barr - Physco Derek
Lindsay McKeon As Taylor James
Colin Fickes As Jimmy Edwards
Amber Wallace As Glenda Farrell
Katherine Bailess As Erica Marsh
Rick Fox As Daunte
Elisabeth Harnois As Shelly Simon
Michael Trucco As Cooper Lee
Kevin Kilner As Larry Sawyer
Sheryl Lee As Ellie Harp
Austin Nichols As Julian
Daphne Zuniga As Victoria Davis
Joe Manganiello As Owen Morello
Robbie Jones As Quentin
Kelsey Chow As Gigi Silveri
Ashley Rickards As Samantha Walker
Michaela McManus As Lindsey Strauss
Kieren Hutchison As Andy Hargrove
Bryan Greenberg As Jake Jagielski
Cullen Moss As Junk
Vaughn Wilson As Fergie
